FORMULATION OF AN ORAL EMULSION FOR THE DELIVERY OF ACTIVE SUBSTANCES CONTAINED IN Atriplex halimus L. LEAVES
DOI:
https://doi.org/10.4314/jfas.v12i1S.3Keywords:
Atriplex halimus; Creaming index; Emulsion; Rheology; Stability.Abstract
This work focuses on the formulation of an oral emulsion for the vectorization of active substances contained in the leaf extract of A. halimus. In order to optimize the formulation parameters of the double emulsion, a complete factorial design of 9 experiments was used. Microscopic observation, which indicates a structure, composed of spherical droplets with well-delimited edges dispersed in the continuous phase. The size of the laser particles indicates average lipid droplet diameters of about 10 µm. Zeta potential values are greater than -30 mV, indicating the electrical stability of dispersed systems. The rheological study showed that viscosity is influenced by the amount of xanthan gum, oil and gum arabic. Storage stability at different temperatures showed that some formulations are more stable than others.
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References
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[15] Hamed M, Chin Ping T, Nazimah S.A. H, Salmah Y. Effect of Arabic gum, xanthan gum and orange oil contents on ζ-potential, conductivity, stability, size index and pH of orange beverage emulsion. Colloids and Surfaces A: Physicochem. Eng. Aspects., 2008, 315, 47–56.
[16] Bouyer E., Mekhloufi G., Le Potier I., De Kerdaniel T DUF., Grossiord J L., Rosilio V., Agnely F . J. Colloid Interface Sci. 2011, 354, 467-477. DOI: 10.1016 / j.jcis.2010.11.0.019
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[18] Samil Kök M, Hill S.E, Mitchell, J.R. A comparison of the rheologicalbehaviour of the crude and refined locust bean gum preparations during thermal processing. Carbohydrate Polymers., 1999, 38, 261–265.
[2] Chikhi I., Allali H., Dib M. E. A., Medjdoub H., Tabti B. Asian Pacific Journal of Tropical Disease. 2014, 4(3), 181-184. DOI:10.1016%2FS2222-1808(14)60501-6
[3] Benarba B., Belabid L., Righi K., Bekkar A., Elouissi M., Khaldi, A., Hamimed A. Jrnl. of ethnopharmacology. 2015, 175, 626-637. DOI: 10.1016 / j.jep.2015.09.030
[4] Emam S. S. Jrnl. Nat Prod. 2011, 4, 25- 41. DOI : 10.3923/rjmp.2016.10.18
[5] Beloued A. Plantes médicinales d'Algérie. In office des Publications Universitaires, Algers , 2001, 284 p.
[6] AL-ACHI A. Herbs that affect blood glucose levels. Women’s Health in Primary Care., 2005, 8, 325-330.
[7] Pei Y. Q. A . Epilepsia. 1983, 24(2), 177-182.DOI: 10.1111/j.1528-1157.1983.tb04877.x
[8] Otal J., Orengo J., Quiles A., Hevia M. L., Fuentes F. Small ruminant research. 2010, 91(2), 208- 214. DOI: 10.1016 / j.smallrumres.2010.03.016
[9] Boussaid M., Ben Fadhel N., Zaouali Y., Ben Salah A., Abdelkefi A. Cahiers Options Méditerranéennes. 2004, 62, 55-59. DOI : 2002/10/29-2002/11/01
[10] Bylka W., Stobiecki M., Franski R. Acta Physiologiae Plantarum. 2001, 23 (3), 285-290. DOI: 10.1007/s11738-001-0035-8
[11] Bylka W. Un nouveau diglycoside de flavonol acylé d’Atriplex lttoralis . Acta Phys Plant. 2004., 26 (4), 393 – 398.
[12] Abd El-Rahman H. H, Mohamed M. I, Gehad A. E. A, Awadallah I. M. Ameliorating the anti-nutritional factors effect in Atriplex halimus on sheep and goats by ensiling or polyethylene glycol supplementation. Inter. Jrnl. of Agri and Bio, 2006, 8, 766 –769.
[13] Benhammou N., Bekkara F A., Panovska T K. Comptes Rendus Chimie. 2009, 12, 1259-1266. DOI: 10.1016 / j.crci.2009.02.004
[14] Franclet A, Le Houérou H. N. The Atriplex in Tunisia and in North Africa. FAO, Rome, Italie, Document No. b0020, 1971 , p 249.
[15] Hamed M, Chin Ping T, Nazimah S.A. H, Salmah Y. Effect of Arabic gum, xanthan gum and orange oil contents on ζ-potential, conductivity, stability, size index and pH of orange beverage emulsion. Colloids and Surfaces A: Physicochem. Eng. Aspects., 2008, 315, 47–56.
[16] Bouyer E., Mekhloufi G., Le Potier I., De Kerdaniel T DUF., Grossiord J L., Rosilio V., Agnely F . J. Colloid Interface Sci. 2011, 354, 467-477. DOI: 10.1016 / j.jcis.2010.11.0.019
[17] Tadros T.F. Emulsion Formation, Stability, and Rheology. In Emulsion Formation and Stability. Weinheim: willey –VCH, 2013, pp. 1-10.
[18] Samil Kök M, Hill S.E, Mitchell, J.R. A comparison of the rheologicalbehaviour of the crude and refined locust bean gum preparations during thermal processing. Carbohydrate Polymers., 1999, 38, 261–265.
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Published
2019-10-02
How to Cite
SLAMANI, M.; ZAOUADI, N.; GHARBI, D.; NAIT BACHIR, Y.; HADJ ZIANE-ZAFOUR, A. FORMULATION OF AN ORAL EMULSION FOR THE DELIVERY OF ACTIVE SUBSTANCES CONTAINED IN Atriplex halimus L. LEAVES. Journal of Fundamental and Applied Sciences, [S. l.], v. 12, n. 1S, p. 35–48, 2019. DOI: 10.4314/jfas.v12i1S.3. Disponível em: https://www.jfas.info/index.php/JFAS/article/view/612. Acesso em: 17 may. 2025.
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