FORMULATION OF AN ORAL EMULSION FOR THE DELIVERY OF ACTIVE SUBSTANCES CONTAINED IN Atriplex halimus L. LEAVES

Authors

  • M. Slamani Chemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Saad Dahlab-Blida 1, soumaa 09000 Blida
  • N. Zaouadi Saad dahleb university
  • D. Gharbi Chemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Saad Dahlab-Blida 1, soumaa 09000 Blida
  • Y. Nait Bachir Chemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Saad Dahlab-Blida 1, soumaa 09000 Blida
  • A. Hadj ziane-Zafour Chemical Engineering Laboratory, Process Engineering Department, Faculty of Technology, University of Saad Dahlab-Blida 1, soumaa 09000 Blida

DOI:

https://doi.org/10.4314/jfas.v12i1S.3

Keywords:

Atriplex halimus; Creaming index; Emulsion; Rheology; Stability.

Abstract

This work focuses on the formulation of an oral emulsion for the vectorization of active substances contained in the leaf extract of A. halimus. In order to optimize the formulation parameters of the double emulsion, a complete factorial design of 9 experiments was used. Microscopic observation, which indicates a structure, composed of spherical droplets with well-delimited edges dispersed in the continuous phase. The size of the laser particles indicates average lipid droplet diameters of about 10 µm. Zeta potential values are greater than -30 mV, indicating the electrical stability of dispersed systems. The rheological study showed that viscosity is influenced by the amount of xanthan gum, oil and gum arabic. Storage stability at different temperatures showed that some formulations are more stable than others.

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Published

2019-10-02

How to Cite

SLAMANI, M.; ZAOUADI, N.; GHARBI, D.; NAIT BACHIR, Y.; HADJ ZIANE-ZAFOUR, A. FORMULATION OF AN ORAL EMULSION FOR THE DELIVERY OF ACTIVE SUBSTANCES CONTAINED IN Atriplex halimus L. LEAVES. Journal of Fundamental and Applied Sciences, [S. l.], v. 12, n. 1S, p. 35–48, 2019. DOI: 10.4314/jfas.v12i1S.3. Disponível em: https://www.jfas.info/index.php/JFAS/article/view/612. Acesso em: 24 mar. 2023.