PREPARATION, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL ACTIVITY EVALUATION OF THYME ESSENTIAL OIL FORMULATION TO TREAT SKIN INFECTIONS
Keywords:Thyme; essential oil; antimicrobial activity; skin irritation; cutaneous infections.
The aim of the present study was to develop and evaluate a topical formulation containing Thymus fontanesii Boiss. & Reut essential oil that could serve as an antimicrobial agent for the treatment of various skin diseases caused by bacteria, yeast and dermatophytes. The selected formulation exhibited a significant antimicrobial activity against all tested strains, better consistency, good homogeneity, no skin irritation and good stability for six months at 25 ± 2°C. Our results demonstrate that the formulation could be used safely as topical preparation to treat skin diseases caused by the tested microorganisms into the future.
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